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Rational prediction of immunogenicity clustering through cross-reactivity analysis of thirteen SARS-CoV-2 variants
Liang Z, Tong J, Sun Z, Liu S, Wu J, Wu X, Li T, Yu Y, Zhang L, Zhao C, Lu Q, Nie J, Huang W, Wang Y. Rational prediction of immunogenicity clustering through cross-reactivity analysis of thirteen SARS-CoV-2 variants. J Med Virol. 2024 Jan;96(1):e29314. doi: 10.1002/jmv.29314. PMID: 38163276. -
Functional characterization of AF-04, an afucosylated anti-MARV GP antibody
Zhang M, Zhang Y, Wu H, Wang X, Zheng H, Feng J, Wang J, Luo L, Xiao H, Qiao C, Li X, Zheng Y, Huang W, Wang Y, Wang Y, Shi Y, Feng J, Chen G. Functional characterization of AF-04, an afucosylated anti-MARV GP antibody. Biochim Biophys Acta Mol Basis Dis. 2024 Feb;1870(2):166964. doi: 10.1016/j.bbadis.2023.166964. Epub 2023 Nov 22. Erratum in: Biochim Biophys Acta Mol Basis Dis. 2024 Jun;1870(5):167046. doi: 10.1016/j.bbadis.2024.167046. PMID: 37995774. -
Development of a reporter gene assay for antibody dependent cellular cytotoxicity activity determination of anti-rabies virus glycoprotein antibodies
Wang W, Yu C, Cui Y, Liu C, Yang Y, Xu G, Wu G, Du J, Fu Z, Guo L, Long C, Xia X, Li Y, Wang L, Wang Y. Development of a reporter gene assay for antibody dependent cellular cytotoxicity activity determination of anti-rabies virus glycoprotein antibodies. Microbiol Immunol. 2023 Feb;67(2):69-78. doi: 10.1111/1348-0421.13036. Epub 2022 Nov 27. PMID: 36346082. -
Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
Cao Y, Jian F, Wang J, Yu Y, Song W, Yisimayi A, Wang J, An R, Chen X, Zhang N, Wang Y, Wang P, Zhao L, Sun H, Yu L, Yang S, Niu X, Xiao T, Gu Q, Shao F, Hao X, Xu Y, Jin R, Shen Z, Wang Y, Xie XS. Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution. Nature. 2023 Feb;614(7948):521-529. doi: 10.1038/s41586-022-05644-7. Epub 2022 Dec 19. PMID: 36535326; PMCID: PMC9931576. -
High-throughput saturation mutagenesis generates a high-affinity antibody against SARS-CoV-2 variants using protein surface display assay on a human cell
Yang Y, Liu S, Luo Y, Wang B, Wang J, Li J, Li J, Ye B, Wang Y, Xi JJ. High-throughput saturation mutagenesis generates a high-affinity antibody against SARS-CoV-2 variants using protein surface display assay on a human cell. PLoS Pathog. 2023 Feb 1;19(2):e1011119. doi: 10.1371/journal.ppat.1011119. PMID: 36724179; PMCID: PMC9891525. -
High-throughput screening of spike variants uncovers the key residues that alter the affinity and antigenicity of SARS-CoV-2
Luo Y, Liu S, Xue J, Yang Y, Zhao J, Sun Y, Wang B, Yin S, Li J, Xia Y, Ge F, Dong J, Guo L, Ye B, Huang W, Wang Y, Xi JJ. High-throughput screening of spike variants uncovers the key residues that alter the affinity and antigenicity of SARS-CoV-2. Cell Discov. 2023 Apr 11;9(1):40. doi: 10.1038/s41421-023-00534-2. PMID: 37041132; PMCID: PMC10088716. -
Aptamer-based nanointerferometer enables amplification-free ultrasensitive detection and differentiation of SARS-CoV-2 variants
Chen C, Song X, Yu Y, Wang X, Xu H, Ji W, Ma J, Zhao C, Feng S, Wang Y, Su XD, Wang W. Aptamer-based nanointerferometer enables amplification-free ultrasensitive detection and differentiation of SARS-CoV-2 variants. Anal Chim Acta. 2023 Jun 15;1260:341207. doi: 10.1016/j.aca.2023.341207. Epub 2023 Apr 11. PMID: 37121656; PMCID: PMC10085716. -
Sera from breakthrough infections with SARS-CoV-2 BA.5 or BF.7 showed lower neutralization activity against XBB.1.5 and CH.1.1
Liu S, Liang Z, Nie J, Gao WB, Li X, Zhang L, Yu Y, Wang Y, Huang W. Sera from breakthrough infections with SARS-CoV-2 BA.5 or BF.7 showed lower neutralization activity against XBB.1.5 and CH.1.1. Emerg Microbes Infect. 2023 Dec;12(2):2225638. doi: 10.1080/22221751.2023.2225638. Epub 2023 Jul 12. PMID: 37313604; PMCID: PMC10339773. -
Characterization of a human-mouse chimeric monoclonal antibody targeting rabies virus glycoprotein
Cai M, Hu Z, Yang Y, Mao T, Liu Y, Lu G, Yang F, Qi J, Huang W, Wang Y. Characterization of a human-mouse chimeric monoclonal antibody targeting rabies virus glycoprotein. J Med Virol. 2023 Jul;95(7):e28954. doi: 10.1002/jmv.28954. PMID: 37493180. -
Development of a Bioluminescent Imaging Mouse Model for SARS-CoV-2 Infection Based on a Pseudovirus System
Wu X, Fang N, Liang Z, Nie J, Lang S, Fan C, Liang C, Huang W, Wang Y. Development of a Bioluminescent Imaging Mouse Model for SARS-CoV-2 Infection Based on a Pseudovirus System. Vaccines (Basel). 2023 Jun 22;11(7):1133. doi: 10.3390/vaccines11071133. PMID: 37514949; PMCID: PMC10385336.