-
Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X. Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants. Nature. 2022 Mar;603(7903):919-925. doi: 10.1038/s41586-022-04466-x. Epub 2022 Jan 28. PMID: 35090164; PMCID: PMC8967717. -
A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs
Liu Z, Zhou J, Xu W, Deng W, Wang Y, Wang M, Wang Q, Hsieh M, Dong J, Wang X, Huang W, Xing L, He M, Tao C, Xie Y, Zhang Y, Wang Y, Zhao J, Yuan Z, Qin C, Jiang S, Lu L. A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs. Cell Res. 2022 Mar;32(3):269-287. doi: 10.1038/s41422-022-00612-2. Epub 2022 Jan 19. PMID: 35046518; PMCID: PMC8767042. -
Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies
Cao Y, Wang J, Jian F, Xiao T, Song W, Yisimayi A, Huang W, Li Q, Wang P, An R, Wang J, Wang Y, Niu X, Yang S, Liang H, Sun H, Li T, Yu Y, Cui Q, Liu S, Yang X, Du S, Zhang Z, Hao X, Shao F, Jin R, Wang X, Xiao J, Wang Y, Xie XS. Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies. Nature. 2022 Feb;602(7898):657-663. doi: 10.1038/s41586-021-04385-3. Epub 2021 Dec 23. PMID: 35016194; PMCID: PMC8866119. -
Infectivity and antigenicity of pseudoviruses with high-frequency mutations of SARS-CoV-2 identified in Portugal
Wang HX, Zhang L, Liang ZT, Nie JH, Wu JJ, Li QQ, Ding RX, Zhang Y, Chen GQ, Wang YC, Wang HG, Huang WJ. Infectivity and antigenicity of pseudoviruses with high-frequency mutations of SARS-CoV-2 identified in Portugal. Arch Virol. 2022 Feb;167(2):459-470. doi: 10.1007/s00705-021-05327-0. Epub 2022 Jan 27. PMID: 35083576; PMCID: PMC8791682. -
Multicenter assessment of shotgun metagenomics for pathogen detection
Liu D, Zhou H, Xu T, Yang Q, Mo X, Shi D, Ai J, Zhang J, Tao Y, Wen D, Tong Y, Ren L, Zhang W, Xie S, Chen W, Xing W, Zhao J, Wu Y, Meng X, Ouyang C, Jiang Z, Liang Z, Tan H, Fang Y, Qin N, Guan Y, Gai W, Xu S, Wu W, Zhang W, Zhang C, Wang Y. Multicenter assessment of shotgun metagenomics for pathogen detection. EBioMedicine. 2021 Dec;74:103649. doi: 10.1016/j.ebiom.2021.103649. Epub 2021 Nov 20. PMID: 34814051; PMCID: PMC8608867. -
Standardised neutralising antibody assays are needed for evaluating COVID-19 vaccines
Wang Y. Standardised neutralising antibody assays are needed for evaluating COVID-19 vaccines. EBioMedicine. 2021 Nov;73:103677. doi: 10.1016/j.ebiom.2021.103677. Epub 2021 Nov 3. PMID: 34742128; PMCID: PMC8564504. -
Ten emerging SARS-CoV-2 spike variants exhibit variable infectivity, animal tropism, and antibody neutralization
Zhang L, Cui Z, Li Q, Wang B, Yu Y, Wu J, Nie J, Ding R, Wang H, Zhang Y, Liu S, Chen Z, He Y, Su X, Xu W, Huang W, Wang Y. Ten emerging SARS-CoV-2 spike variants exhibit variable infectivity, animal tropism, and antibody neutralization. Commun Biol. 2021 Oct 13;4(1):1196. doi: 10.1038/s42003-021-02728-4. PMID: 34645933; PMCID: PMC8514557. -
Structure-based analyses of neutralization antibodies interacting with naturally occurring SARS-CoV-2 RBD variants
Zhou Z, Zhang X, Li Q, Fu L, Wang M, Liu S, Wu J, Nie J, Zhang L, Zhao C, Jiang F, An Y, Yu B, Zheng H, Wang Y, Zhao A, Huang W. Unmethylated CpG motif-containing genomic DNA fragments of bacillus calmette-guerin improves immune response towards a DNA vaccine for COVID-19. Vaccine. 2021 Oct 1;39(41):6050-6056. doi: 10.1016/j.vaccine.2021.08.103. Epub 2021 Sep 3. PMID: 34521552; PMCID: PMC8413458. -
Antibody-dependent cellular cytotoxicity response to SARS-CoV-2 in COVID-19 patients
Xu H, Wang B, Zhao TN, Liang ZT, Peng TB, Song XH, Wu JJ, Wang YC, Su XD. Structure-based analyses of neutralization antibodies interacting with naturally occurring SARS-CoV-2 RBD variants. Cell Res. 2021 Oct;31(10):1126-1129. doi: 10.1038/s41422-021-00554-1. Epub 2021 Sep 3. PMID: 34480123; PMCID: PMC8413711. -
A broadly neutralizing humanized ACE2-targeting antibody against SARS-CoV-2 variants
Yu Y, Wang M, Zhang X, Li S, Lu Q, Zeng H, Hou H, Li H, Zhang M, Jiang F, Wu J, Ding R, Zhou Z, Liu M, Si W, Zhu T, Li H, Ma J, Gu Y, She G, Li X, Zhang Y, Peng K, Huang W, Liu W, Wang Y. Antibody-dependent cellular cytotoxicity response to SARS-CoV-2 in COVID-19 patients. Signal Transduct Target Ther. 2021 Sep 24;6(1):346. doi: 10.1038/s41392-021-00759-1. PMID: 34561414; PMCID: PMC8463587.